The African Population and Health Research Center (APHRC) is Africa’s premier research institution generating evidence to drive policy action to improve the health and wellbeing of African people. The safety and health of its 156 employees is a primary consideration in APHRC’s operation, which is driven by the Health and Safety Committee. Employer and employee responsibilities are clearly outlined in the APHRC Policy on Safety and Health. APHRC is committed to a holistic approach to wellbeing that spans care and attention to mental, vocational, social and emotional health. This includes annual check-ups, flexiwork, counselling, gym subsidies, support for breastfeeding women (recognized by the Ministry of Health) as well as new office policies addressing COVID-19. A milestone is the recent construction of a creche to support staff with young children. Staff members also make commitments to community service as part of their annual performance agreement.